Journal: bioRxiv

Article Title: Development of visual cortex in human neonates are selectively modified by postnatal experience

doi: 10.1101/2022.03.16.484671

Figure Lengend Snippet: The innate functional organization of ventral cortex within 1 day after birth and its development in the first month of age in human newborns. (a) The pairwise correlation matrix describes the functional correlations among 34 ROIs across hemispheres in ventral cortex. (b) The scatter graph illustrates the correlation coefficients ( r ) between 34 pairs of bilateral homotopic areas, and the dash line indicates the corrected threshold (Bonferroni corrected p < 0.01). (c) The box graph depicts the comparison between homotopic and non-homotopic connections at birth. (d) Multidimensional scaling and community groups obtained from the pairwise ipsilateral connections between 34 ROIs in right ventral cortex and the corresponding projection on the cortical surface. The color of the nodes in (d) indicate the cluster identity in the community structure analysis and color of the lines connecting the nodes indicate the functional correlation ( r value) between two nodes within the right hemisphere. The correlation coefficient maps between the homotopic correlation and PMA (e) or postnatal time (f) in 34 ROIs, the maroon contours indicated the significant regions after FDR correlation (FDR q < 0.05). The correlation between network measurements of the right hemisphere and PMA (g) or postnatal time (h). The values in the bracket indicate the partial correlation coefficients in (h) between the network properties and postnatal time when controlling for PMA. * p < 0.05, *** p < 0.001.

Article Snippet: Non-classical multi-dimensional scaling (MDS) was carried on the distance matrix with Kruskal’s normalized criterion in MATLAB.

Techniques: Functional Assay, Comparison